The freeze-drying machine originated in the 1820s vacuum freeze-drying technology has experienced decades of ups and downs and wandering in the last 20 years has made considerable progress. In the 21st century, vacuum freeze-drying technology by virtue of other drying methods can not match the advantages of more and more people of all ages, in addition to medicine, biological products, food, blood products, active substances in the field of widely used, the application scale and field Still expanding. To this end, vacuum freeze drying will become an important application of the 21st century technology.